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        <div id="content-top1">Page 54 - LG Aiom 2018</div>
        <div id="content-top2">P. 54</div>
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    <pre style="white-space:pre-line"><code>TRATTAMENTO: STADIO I-II                                                                                                   Figure                                          NEOPLASIE DELLâ€™UTERO: ENDOMETRIO E CERVICE

    Stage I/II FIGO     Ia1 e Ia 2 senza           Conizzazione* o                                                                                      SECONDA PARTE: NEOPLASIE DELLA CERVICE
                       infiltrazione spazi      Isterectomia semplice
                                             Nessuna terapia adiuvante
                         linfovascolari
                                               Conizzazione* o
                     Ia 2 con infiltrazione    Trachelectomia* ;
                           degli spazi         Isterectomia semplice con
                                               linfoadenectomia pelvica e
                      linfovascolari, Ib1      lomboaraortica;
                                               Radioterapia esclusiva .
                                               Nessuna terapia adiuvante

54                                           ï‚§ Radiochemioterapia concomitante

                     Ib2-IIB                     esclusiva
                                             ï‚§ Chemioterapia neoadiuvante a base di

                                                 platino x 3 cicli seguita da isterectomia

                                                 radicale con linfoadenectomia pelvica e

                                                 lomboaortica**
                                             ï‚§ Terapia adiuvante in casi selezionati ***

    * In pazienti desiderose di prole con linfonodi negativi                                                                                                                                       LINEE GUIDA
    ** La chemioterapia neoadiuvante, largamente impiegata in Italia, attende conferma della sua validitÃ  dallo studio EORTC in corso e va                                                      2018

        presa in considerazione in casi selezionati
    *** In caso di linfonodi positivi, parametri positivi o margini positivi effettuare RT-CHT adiuvante; in caso di presenza di almeno 2 di 3

        fattori di rischio tra infiltrazione stomale &gt;50%, infiltrazione degli spazi linfovascolari o tumore &gt;2 cm effettuare RT adiuvante</code></pre>
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